ORAL GRAFT-VERSUS-HOST DISEASES

Oral features of graft-versus-host disease*

Chronic graft-versus-host disease (cGVHD) is a late complication of allogeneic hematopoietic stem cell transplant (HSCT), occurring in 18% to 70% of recipients.1-3 The oral tissues may be involved in up to 90% of the patients that present cGVHD in other organs.4-10 Oral mucosa lesions and salivary gland dysfunction are the main manifestations of oral cGVHD, but a reduction of the mouth opening ...

Graft-versus-host disease or graft-versus-host-like syndrome.

How we treat oral chronic graft-versus-host disease.

Chronic graft-versus-host disease (cGVHD) is a major complication of allogeneic hematopoietic cell transplantation that is associated with a diminished quality of life. The oral cavity is frequently affected, with a wide variety of signs and symptoms that can result in significant short- and long-term complications ranging from mucosal sensitivity and limited oral intake to secondary malignancy...

Oral lesions in paediatric patients with graft-versus-host disease.

AIM This work aims at assessing and describing the most frequent clinical manifestations of the Graft-versus- Host Disease (GvHD) in the oral and maxillofacial region in paediatric patients affected by neoplastic or non neoplastic haematologic disorders who undergo specific haematopoietic stem cell transplantation (HSCT) protocols, with a view to detecting the potential pathological modificatio...

Graft-versus-host disease affecting oral cavity. A review

Graft versus host disease (GVHD) is one of the most frequent and serious complications of hematopoietic stem cell transplantation, and is regarded as the leading cause of late mortality unrelated to the underlying malignant disease. GVHD is an autoimmune and alloimmune disorder that usually affects multiple organs and tissues, and exhibits a variable clinical course. It can manifest in either a...